POG 9406


Phase III Randomized Study of High Versus Standard Dose Methotrexate and High Dose Cytarabine and Asparaginase Rescue Versus Standard Dose Cytarabine and Teniposide During Intensive Continuation and Consolidation in Children with High Risk Acute Lymphocytic Leukemia: An ALinC #16 Study.

This trial on the cancer.gov site.

Treatment for high-risk ALL, defined as

Protocol initiated: (?), 540 patients over approximately 3.8 years

Study Chair: Joanne Kurtzberg 919-684-8963

Specific Aims:


Protocol outline:

4 arms of treatment:

POG 9406


Compared with the current CCG higher risk protocol (CCG 1961), POG 9406 utilizes the following not in the CCG trial:

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Last Updated 4/06

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